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Assay Detail

CHEMBL3067706

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Binding
Inhibition of Spinacia oleracea (spinach) glutamine synthetase activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Spinacia oleracea
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glutamine synthetase (CHEMBL2366402)
Type SINGLE PROTEIN
Organism Spinacia oleracea

Publication

Plant P5C reductase as a new target for aminomethylenebisphosphonates.
Forlani G, Giberti S, Berlicki L, Petrollino D, Kafarski P.
J Agric Food Chem (2007) 55 : 4340 -4347
PubMed 17474756 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.26 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL55518 (3,5-DICHLOROPHENYLAMINO)METHYLENEDIPHOSPHONIC ACID 1 4.52
CHEMBL95764 GLYPHOSATE 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL55518 (3,5-DICHLOROPHENYLAMINO)METHYLENEDIPHOSPHONIC ACID IC50 = 30000.0 nM 4.52
CHEMBL95764 GLYPHOSATE IC50 = 100000.0 nM 4.00