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Assay Detail

CHEMBL3068445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against Homo sapiens (human) HeLa cells after 48 hr by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

In vivo peritoneal antiangiogenesis and in vitro antiproliferative properties of some bischalcone derivatives
Darshan Raj CG, Sarojini BK, Ramakrishna MK, Ramesh SR, Manjunatha H
Med Chem Res (2012) 21 : 453 -458
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.40 4.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL476846 1 4.41
CHEMBL270361 1 4.38
CHEMBL485636 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL476846 IC50 = 39000.0 nM 4.41
CHEMBL270361 IC50 = 42000.0 nM 4.38
CHEMBL485636 IC50 = 110000.0 nM -