Assay Detail
Functional
CHEMBL3068966
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Antioxidant activity assessed as inhibition of DPPH radical formation
8
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis of new series of pyrimido[4,5-b][1,4] benzothiazines as 15-lipoxygenase inhibitors and study of their inhibitory mechanism
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.46 | 4.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2296824 | — | — | 1 | 4.76 |
| CHEMBL437540 | — | — | 2 | 4.16 |
| CHEMBL2296823 | — | — | 1 | - |
| CHEMBL2296822 | — | — | 1 | - |
| CHEMBL2296821 | — | — | 1 | - |
| CHEMBL2296820 | — | — | 1 | - |
| CHEMBL2296819 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2296824 | — | IC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL437540 | — | IC50 | = | 69600.0 | nM | 4.16 |
| CHEMBL437540 | — | IC50 | = | 141600.0 | nM | - |
| CHEMBL2296823 | — | IC50 | = | 357300.0 | nM | - |
| CHEMBL2296822 | — | IC50 | = | 668700.0 | nM | - |
| CHEMBL2296821 | — | IC50 | = | 599300.0 | nM | - |
| CHEMBL2296820 | — | IC50 | = | 620700.0 | nM | - |
| CHEMBL2296819 | — | IC50 | = | 310900.0 | nM | - |