Assay Detail
Binding
CHEMBL3069077
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Arabidopsis thaliana IspC expressed in Escherichia coli after 40 min by spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Arabidopsis thaliana |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic (CHEMBL2285354) ↗| Type | SINGLE PROTEIN |
| Organism | Arabidopsis thaliana |
Publication
In search of new herbicidal inhibitors of the non-mevalonate pathway.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.23 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203125 | FOSMIDOMYCIN | 3.0 | 1 | 7.00 |
| CHEMBL2289494 | — | — | 1 | 4.47 |
| CHEMBL2289495 | — | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203125 | FOSMIDOMYCIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL2289494 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL2289495 | — | IC50 | = | 59000.0 | nM | 4.23 |