Assay Detail
Binding
CHEMBL3069086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of protoporphyrinogen-9 oxidase in Echinochloa esculenta seed after 5 min by Dixon plot analysis
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Echinochloa esculenta |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Protoporphyrinogen oxidase, chloroplastic (CHEMBL2366510) ↗| Type | SINGLE PROTEIN |
| Organism | Oryza sativa subsp. japonica |
Publication
Protoporphyrinogen-IX Oxidase Inhibition by N-(2, 4, 5-Trisubstituted phenyl)-3, 4, 5, 6-tetrahydrophthalimides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.92 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2269733 | — | — | 1 | 9.10 |
| CHEMBL2286887 | — | — | 1 | 8.80 |
| CHEMBL2269750 | — | — | 1 | 8.70 |
| CHEMBL2269734 | — | — | 1 | 8.50 |
| CHEMBL2133606 | FLUMIOXAZIN | — | 1 | 8.40 |
| CHEMBL2269736 | — | — | 1 | 8.30 |
| CHEMBL2269741 | — | — | 1 | 8.10 |
| CHEMBL2269745 | CHLOROPHTHALIUM | — | 1 | 7.90 |
| CHEMBL2286885 | — | — | 1 | 5.90 |
| CHEMBL2286886 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2269733 | — | IC50 | = | 0.7943 | nM | 9.10 |
| CHEMBL2286887 | — | IC50 | = | 1.585 | nM | 8.80 |
| CHEMBL2269750 | — | IC50 | = | 1.995 | nM | 8.70 |
| CHEMBL2269734 | — | IC50 | = | 3.162 | nM | 8.50 |
| CHEMBL2133606 | FLUMIOXAZIN | IC50 | = | 3.981 | nM | 8.40 |
| CHEMBL2269736 | — | IC50 | = | 5.012 | nM | 8.30 |
| CHEMBL2269741 | — | IC50 | = | 7.943 | nM | 8.10 |
| CHEMBL2269745 | CHLOROPHTHALIUM | IC50 | = | 12.59 | nM | 7.90 |
| CHEMBL2286885 | — | IC50 | = | 1258.93 | nM | 5.90 |
| CHEMBL2286886 | — | IC50 | = | 3162.28 | nM | 5.50 |