Assay Detail
Binding
CHEMBL3070435
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Inhibition of Saccharomyces cerevisiae chitin synthase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pharmacophore-based 3D-QSAR study of fungal chitin synthase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.03 | 4.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1098239 | — | — | 1 | 4.03 |
| CHEMBL2295882 | — | — | 1 | - |
| CHEMBL287855 | — | — | 1 | - |
| CHEMBL144626 | — | — | 1 | - |
| CHEMBL33943 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1098239 | — | IC50 | = | 94188.96 | nM | 4.03 |
| CHEMBL2295882 | — | IC50 | = | 824138.12 | nM | - |
| CHEMBL287855 | — | IC50 | = | 297851.64 | nM | - |
| CHEMBL144626 | — | IC50 | = | 372391.71 | nM | - |
| CHEMBL33943 | — | IC50 | = | 372391.71 | nM | - |