Assay Detail
Binding
CHEMBL3072452
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Inhibition of Oryza sativa (rice) PDHc by spectrophotometric assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryza sativa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
α-(Substituted-phenoxyacetoxy)-α-heterocyclylmethylphosphonates: synthesis, herbicidal activity, inhibition on pyruvate dehydrogenase complex (PDHc), and application as postemergent herbicide against broadleaf weeds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.14 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2289238 | — | — | 1 | 6.54 |
| CHEMBL2289237 | — | — | 1 | 5.49 |
| CHEMBL2289236 | — | — | 1 | 4.72 |
| CHEMBL2271092 | — | — | 1 | 4.54 |
| CHEMBL2253413 | — | — | 1 | 4.39 |
| CHEMBL2227911 | CLACYFOS | — | 1 | - |
| CHEMBL2253447 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2289238 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL2289237 | — | IC50 | = | 3260.0 | nM | 5.49 |
| CHEMBL2289236 | — | IC50 | = | 18870.0 | nM | 4.72 |
| CHEMBL2271092 | — | IC50 | = | 29140.0 | nM | 4.54 |
| CHEMBL2253413 | — | IC50 | = | 41140.0 | nM | 4.39 |
| CHEMBL2227911 | CLACYFOS | IC50 | = | 867330.0 | nM | - |
| CHEMBL2253447 | — | IC50 | = | 703880.0 | nM | - |