Assay Detail
Binding
CHEMBL3072560
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Binding affinity to Drosophila melanogaster EcR
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Drosophila melanogaster |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.60 | 7.34 |
| Ki | 1 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224128 | 20-HYDROXYECDYSONE | 2.0 | 1 | 7.34 |
| CHEMBL226968 | TEBUFENOZIDE | — | 1 | 6.60 |
| CHEMBL255034 | MAKISTERONE A | — | 1 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224128 | 20-HYDROXYECDYSONE | IC50 | = | 45.71 | nM | 7.34 |
| CHEMBL226968 | TEBUFENOZIDE | Ki | = | 251.19 | nM | 6.60 |
| CHEMBL255034 | MAKISTERONE A | IC50 | = | 1380.38 | nM | 5.86 |