Assay Detail
Functional
CHEMBL3072746
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Antimicrobial activity against Aspergillus niger assessed as growth inhibition after 24 hr by cup plate method
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aspergillus niger |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis antimicrobial and anticancer activity of N-arylmethylidene-piperazine-1-carbothiohydrazide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.61 | 5.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2296997 | — | — | 1 | 5.81 |
| CHEMBL2297230 | — | — | 1 | 5.79 |
| CHEMBL2296995 | — | — | 1 | 5.71 |
| CHEMBL2296998 | — | — | 1 | 5.68 |
| CHEMBL2296999 | — | — | 1 | 5.67 |
| CHEMBL2297001 | — | — | 1 | 5.66 |
| CHEMBL2297002 | — | — | 1 | 5.48 |
| CHEMBL2296996 | — | — | 1 | 5.45 |
| CHEMBL2297003 | — | — | 1 | 5.42 |
| CHEMBL2297000 | — | — | 1 | 5.42 |
| CHEMBL106 | FLUCONAZOLE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2296997 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL2297230 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL2296995 | — | IC50 | = | 1970.0 | nM | 5.71 |
| CHEMBL2296998 | — | IC50 | = | 2090.0 | nM | 5.68 |
| CHEMBL2296999 | — | IC50 | = | 2140.0 | nM | 5.67 |
| CHEMBL2297001 | — | IC50 | = | 2210.0 | nM | 5.66 |
| CHEMBL2297002 | — | IC50 | = | 3320.0 | nM | 5.48 |
| CHEMBL2296996 | — | IC50 | = | 3550.0 | nM | 5.45 |
| CHEMBL2297003 | — | IC50 | = | 3790.0 | nM | 5.42 |
| CHEMBL2297000 | — | IC50 | = | 3760.0 | nM | 5.42 |
| CHEMBL106 | FLUCONAZOLE | IC50 | > | 10000.0 | nM | - |