Assay Detail
Functional
CHEMBL3072748
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimicrobial activity against Vibrio cholerae assessed as growth inhibition after 24 hr by cup-plate method
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vibrio cholerae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis antimicrobial and anticancer activity of N-arylmethylidene-piperazine-1-carbothiohydrazide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.94 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | 4.0 | 1 | 6.70 |
| CHEMBL2296999 | — | — | 1 | 6.22 |
| CHEMBL2297002 | — | — | 1 | 6.11 |
| CHEMBL2296997 | — | — | 1 | 6.07 |
| CHEMBL2297000 | — | — | 1 | 5.93 |
| CHEMBL2297230 | — | — | 1 | 5.86 |
| CHEMBL2296998 | — | — | 1 | 5.82 |
| CHEMBL2296996 | — | — | 1 | 5.80 |
| CHEMBL2296995 | — | — | 1 | 5.78 |
| CHEMBL2297001 | — | — | 1 | 5.65 |
| CHEMBL2297003 | — | — | 1 | 5.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2296999 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL2297002 | — | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL2296997 | — | IC50 | = | 860.0 | nM | 6.07 |
| CHEMBL2297000 | — | IC50 | = | 1170.0 | nM | 5.93 |
| CHEMBL2297230 | — | IC50 | = | 1380.0 | nM | 5.86 |
| CHEMBL2296998 | — | IC50 | = | 1530.0 | nM | 5.82 |
| CHEMBL2296996 | — | IC50 | = | 1590.0 | nM | 5.80 |
| CHEMBL2296995 | — | IC50 | = | 1660.0 | nM | 5.78 |
| CHEMBL2297001 | — | IC50 | = | 2230.0 | nM | 5.65 |
| CHEMBL2297003 | — | IC50 | = | 3570.0 | nM | 5.45 |