Assay Detail
Functional
CHEMBL3072749
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Antimicrobial activity against Bacillus subtilis NCIM 2921 assessed as growth inhibition after 24 hr by serial double dilution method
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus subtilis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis antimicrobial and anticancer activity of N-arylmethylidene-piperazine-1-carbothiohydrazide
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.96 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2296999 | — | — | 1 | 6.89 |
| CHEMBL2296997 | — | — | 1 | 6.50 |
| CHEMBL2296998 | — | — | 1 | 6.18 |
| CHEMBL2297001 | — | — | 1 | 6.03 |
| CHEMBL2297002 | — | — | 1 | 6.01 |
| CHEMBL2297230 | — | — | 1 | 5.86 |
| CHEMBL2296995 | — | — | 1 | 5.79 |
| CHEMBL2297003 | — | — | 1 | 5.77 |
| CHEMBL2297000 | — | — | 1 | 5.75 |
| CHEMBL2296996 | — | — | 1 | 5.46 |
| CHEMBL8 | CIPROFLOXACIN | 4.0 | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2296999 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL2296997 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL2296998 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL2297001 | — | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL2297002 | — | IC50 | = | 980.0 | nM | 6.01 |
| CHEMBL2297230 | — | IC50 | = | 1380.0 | nM | 5.86 |
| CHEMBL2296995 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL2297003 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL2297000 | — | IC50 | = | 1780.0 | nM | 5.75 |
| CHEMBL2296996 | — | IC50 | = | 3490.0 | nM | 5.46 |
| CHEMBL8 | CIPROFLOXACIN | IC50 | = | 4700.0 | nM | 5.33 |