Assay Detail
Functional
CHEMBL3073516
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Cytotoxicity against Homo sapiens (human) A549 cells assessed as cell viability after 72 hr by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potential cytotoxic and apoptosis inducing agents: synthesis and evaluation of methoxy-substituted chalcones against human lung and cervical cancers
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 7.01 | 7.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL144152 | — | — | 1 | 7.36 |
| CHEMBL2296853 | — | — | 1 | 7.10 |
| CHEMBL2296852 | — | — | 1 | 7.06 |
| CHEMBL2296847 | — | — | 1 | 7.00 |
| CHEMBL2296850 | — | — | 1 | 6.96 |
| CHEMBL2296851 | — | — | 1 | 6.96 |
| CHEMBL2296854 | — | — | 1 | 6.95 |
| CHEMBL2296848 | — | — | 1 | 6.69 |
| CHEMBL2296846 | — | — | 1 | - |
| CHEMBL2296849 | — | — | 1 | - |
| CHEMBL2296855 | — | — | 1 | - |
| CHEMBL2296856 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL144152 | — | IC50 | = | 43.6 | nM | 7.36 |
| CHEMBL2296853 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL2296852 | — | IC50 | = | 87.3 | nM | 7.06 |
| CHEMBL2296847 | — | IC50 | = | 101.2 | nM | 7.00 |
| CHEMBL2296850 | — | IC50 | = | 108.3 | nM | 6.96 |
| CHEMBL2296851 | — | IC50 | = | 108.3 | nM | 6.96 |
| CHEMBL2296854 | — | IC50 | = | 113.5 | nM | 6.95 |
| CHEMBL2296848 | — | IC50 | = | 202.2 | nM | 6.69 |
| CHEMBL2296846 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2296849 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2296855 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2296856 | — | IC50 | > | 100000.0 | nM | - |