Assay Detail
Functional
CHEMBL3074476
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium assessed as effect on rate measured immediately by isometric transducer analysis in absence of benzalkonium/prazosin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Cardiac atrium |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Polyamines May Modulate Both G Protein-Coupled Receptors and G Proteins
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 9.01 | 9.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL130835 | PIPERTRAMINE AMIDE | — | 1 | 9.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL130835 | PIPERTRAMINE AMIDE | EC50 | = | 0.9772 | nM | 9.01 |