Assay Detail
Functional
CHEMBL3075853
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Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, anticancer and antibacterial activities of piperine analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.03 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2296887 | — | — | 1 | 6.13 |
| CHEMBL2296611 | — | — | 1 | 6.06 |
| CHEMBL2296885 | — | — | 1 | 6.03 |
| CHEMBL2296886 | — | — | 1 | 6.02 |
| CHEMBL43185 | PIPERINE | 2.0 | 1 | 6.00 |
| CHEMBL1094074 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2296887 | — | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL2296611 | — | IC50 | = | 870.0 | nM | 6.06 |
| CHEMBL2296885 | — | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL2296886 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL43185 | PIPERINE | IC50 | = | 990.0 | nM | 6.00 |
| CHEMBL1094074 | — | IC50 | = | 1089.0 | nM | 5.96 |