Assay Detail
Functional
CHEMBL3076581
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Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as cell viability after 24 hr by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial and anticancer effects of some 2-(substitutedsulfanyl)-N-(5-methyl-isoxazol-3-yl)acetamide derivatives
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.29 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1391713 | — | — | 1 | 7.05 |
| CHEMBL2283204 | — | — | 1 | 6.66 |
| CHEMBL1602103 | — | — | 1 | 6.40 |
| CHEMBL2283205 | — | — | 1 | 6.17 |
| CHEMBL1517744 | — | — | 1 | 6.13 |
| CHEMBL2283207 | — | — | 1 | 5.99 |
| CHEMBL1486032 | — | — | 1 | 5.95 |
| CHEMBL1352217 | — | — | 1 | 5.95 |
| CHEMBL1361345 | — | — | 1 | - |
| CHEMBL2283206 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1391713 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL2283204 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL1602103 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL2283205 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL1517744 | — | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL2283207 | — | IC50 | = | 1020.0 | nM | 5.99 |
| CHEMBL1486032 | — | IC50 | = | 1130.0 | nM | 5.95 |
| CHEMBL1352217 | — | IC50 | = | 1130.0 | nM | 5.95 |
| CHEMBL1361345 | — | IC50 | - | — | - | |
| CHEMBL2283206 | — | IC50 | - | — | - |