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Assay Detail

CHEMBL3077324

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Hepatitis C virus NS5B polymerase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

RNA-directed RNA polymerase (CHEMBL4296320)
Type SINGLE PROTEIN
Organism Hepacivirus hominis

Publication

Design, synthesis, and biological evaluation of new 4-thiazolidinone derivatives substituted with benzimidazole ring as potential chemotherapeutic agents
Masoud GN, Youssef AM, Abdel Khalek MM, Abdel Wahab AE, Labouta IM, Hazzaa AAB
Med Chem Res (2013) 22 : 707 -725
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL202580 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL202580 IC50 = 200.0 nM 6.70