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Assay Detail

CHEMBL3082979

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Phytotoxicity against Physalis ixocarpa assessed as inhibition of root development during seeding stage after 120 hr
12
Total Activities
12
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Physalis ixocarpa
Confidence 1 — Organism
Curated By Autocuration

Target

Physalis ixocarpa (CHEMBL2366827)
Type ORGANISM
Organism Physalis ixocarpa

Publication

Plant growth inhibitory activity of p-hydroxyacetophenones and tremetones from Chilean endemic Baccharis species and some analogous: a comparative study.
Céspedes CL, Uchoa A, Salazar JR, Perich F, Pardo F.
J Agric Food Chem (2002) 50 : 2283 -2292
PubMed 11929285 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 4.75 5.00
I50 4 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2271141 1 5.00
CHEMBL201083 4-HYDROXYACETOPHENONE 1 4.97
CHEMBL2271142 4-HYDROXY TREMETONE 1 4.90
CHEMBL2271144 10,11-EPOXY TREMETONE 1 4.80
CHEMBL463974 TREMETONE 1 4.73
CHEMBL2271143 10,11-DIHYDRO TREMETONE 1 4.72
CHEMBL401912 P-METHOXY-ACETOPHENONE 1 4.69
CHEMBL2271140 4-ACETYL TREMETONE 1 4.15
CHEMBL274467 ACETOPHENONE 1 -
CHEMBL2271145 4-(ACETATE)ACETOPHENONE 1 -
CHEMBL401928 1 -
CHEMBL1512620 PICEIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2271141 IC50 = 9900.0 nM 5.00
CHEMBL201083 4-HYDROXYACETOPHENONE IC50 = 10800.0 nM 4.97
CHEMBL2271142 4-HYDROXY TREMETONE IC50 = 12700.0 nM 4.90
CHEMBL2271144 10,11-EPOXY TREMETONE IC50 = 15700.0 nM 4.80
CHEMBL463974 TREMETONE IC50 = 18600.0 nM 4.73
CHEMBL2271143 10,11-DIHYDRO TREMETONE IC50 = 19100.0 nM 4.72
CHEMBL401912 P-METHOXY-ACETOPHENONE IC50 = 20500.0 nM 4.69
CHEMBL2271140 4-ACETYL TREMETONE IC50 = 70100.0 nM 4.15
CHEMBL274467 ACETOPHENONE I50 - -
CHEMBL2271145 4-(ACETATE)ACETOPHENONE I50 - -
CHEMBL401928 I50 - -
CHEMBL1512620 PICEIN I50 - -