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Assay Detail

CHEMBL3083006

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Functional
Inhibition of H+ uptake in Spinacia oleracea (spinach) chloroplasts
19
Total Activities
12
Compounds Tested
3
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Spinacia oleracea
Confidence 1 — Organism
Curated By Autocuration

Target

Spinacia oleracea (CHEMBL612824)
Type ORGANISM
Organism Spinacia oleracea

Publication

Plant growth inhibitory activity of p-hydroxyacetophenones and tremetones from Chilean endemic Baccharis species and some analogous: a comparative study.
Céspedes CL, Uchoa A, Salazar JR, Perich F, Pardo F.
J Agric Food Chem (2002) 50 : 2283 -2292
PubMed 11929285 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Inhibition 7 - -
IC50 6 4.40 4.86
I50 6 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2271141 2 4.86
CHEMBL2271142 4-HYDROXY TREMETONE 2 4.69
CHEMBL2271144 10,11-EPOXY TREMETONE 2 4.39
CHEMBL401912 P-METHOXY-ACETOPHENONE 2 4.18
CHEMBL463974 TREMETONE 2 4.15
CHEMBL201083 4-HYDROXYACETOPHENONE 2 4.13
CHEMBL2271140 4-ACETYL TREMETONE 2 -
CHEMBL2271145 4-(ACETATE)ACETOPHENONE 1 -
CHEMBL401928 1 -
CHEMBL1512620 PICEIN 1 -
CHEMBL2271143 10,11-DIHYDRO TREMETONE 1 -
CHEMBL274467 ACETOPHENONE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2271141 IC50 = 13800.0 nM 4.86
CHEMBL2271142 4-HYDROXY TREMETONE IC50 = 20400.0 nM 4.69
CHEMBL2271144 10,11-EPOXY TREMETONE IC50 = 40700.0 nM 4.39
CHEMBL401912 P-METHOXY-ACETOPHENONE IC50 = 65700.0 nM 4.18
CHEMBL463974 TREMETONE IC50 = 70700.0 nM 4.15
CHEMBL201083 4-HYDROXYACETOPHENONE IC50 = 74500.0 nM 4.13
CHEMBL2271140 4-ACETYL TREMETONE I50 - -
CHEMBL2271145 4-(ACETATE)ACETOPHENONE I50 - -
CHEMBL401928 I50 - -
CHEMBL1512620 PICEIN I50 - -
CHEMBL2271141 Inhibition - % -
CHEMBL2271140 4-ACETYL TREMETONE Inhibition - % -
CHEMBL2271142 4-HYDROXY TREMETONE Inhibition - % -
CHEMBL2271144 10,11-EPOXY TREMETONE Inhibition - % -
CHEMBL463974 TREMETONE Inhibition - % -
CHEMBL401912 P-METHOXY-ACETOPHENONE Inhibition - % -
CHEMBL201083 4-HYDROXYACETOPHENONE Inhibition - % -
CHEMBL2271143 10,11-DIHYDRO TREMETONE I50 - -
CHEMBL274467 ACETOPHENONE I50 - -