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Assay Detail

CHEMBL3083025

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Functional
Phytotoxicity against Lolium multiflorum (Italian ryegrass) assessed as inhibition of seed respiration during germination after 72 hr
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Lolium multiflorum
Confidence 1 — Organism
Curated By Autocuration

Target

Lolium multiflorum (CHEMBL2367274)
Type ORGANISM
Organism Lolium multiflorum

Publication

Plant growth inhibitory activity of p-hydroxyacetophenones and tremetones from Chilean endemic Baccharis species and some analogous: a comparative study.
Céspedes CL, Uchoa A, Salazar JR, Perich F, Pardo F.
J Agric Food Chem (2002) 50 : 2283 -2292
PubMed 11929285 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.42 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2271141 1 4.75
CHEMBL2271142 4-HYDROXY TREMETONE 1 4.41
CHEMBL401912 P-METHOXY-ACETOPHENONE 1 4.40
CHEMBL201083 4-HYDROXYACETOPHENONE 1 4.39
CHEMBL2271144 10,11-EPOXY TREMETONE 1 4.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2271141 IC50 = 18000.0 nM 4.75
CHEMBL2271142 4-HYDROXY TREMETONE IC50 = 39000.0 nM 4.41
CHEMBL401912 P-METHOXY-ACETOPHENONE IC50 = 40000.0 nM 4.40
CHEMBL201083 4-HYDROXYACETOPHENONE IC50 = 41000.0 nM 4.39
CHEMBL2271144 10,11-EPOXY TREMETONE IC50 = 67900.0 nM 4.17