Assay Detail
Binding
CHEMBL3088544
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Inhibition of sphingosine kinase 1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.43 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3086782 | — | — | 1 | 6.00 |
| CHEMBL1442934 | SAFINGOL | 2.0 | 1 | 5.30 |
| CHEMBL2376441 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3086782 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL1442934 | SAFINGOL | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL2376441 | — | Ki | = | 10000.0 | nM | 5.00 |