Assay Detail
Functional
CHEMBL3088899
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Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.82 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469695 | — | — | 1 | 6.38 |
| CHEMBL1598051 | — | — | 1 | 5.77 |
| CHEMBL3085788 | — | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469695 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL1598051 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL3085788 | — | IC50 | = | 4900.0 | nM | 5.31 |