Assay Detail
Binding
CHEMBL3089088
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cells
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of a (18)F-labeled diarylpyrazole glycoconjugate for the imaging of NTS1-positive tumors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.18 | 9.54 |
| Kd | 1 | 9.29 | 9.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342252 | — | — | 1 | 9.54 |
| CHEMBL407196 | NEUROTENSIN | — | 1 | 9.29 |
| CHEMBL3086356 | — | — | 1 | 9.01 |
| CHEMBL3040381 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342252 | — | Ki | = | 0.29 | nM | 9.54 |
| CHEMBL407196 | NEUROTENSIN | Kd | = | 0.51 | nM | 9.29 |
| CHEMBL3086356 | — | Ki | = | 0.98 | nM | 9.01 |
| CHEMBL3040381 | — | Ki | = | 1.0 | nM | 9.00 |