Assay Detail
Functional
CHEMBL3089312
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Photocytotoxicity against human MCF7 cells expressing low level of folate receptor assessed as cell viability incubated for 24 hrs followed by halogen light illumination measured after 20 mins by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Preparation and in vitro photodynamic activities of folate-conjugated distyryl boron dipyrromethene based photosensitizers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.27 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3087008 | — | — | 1 | 7.22 |
| CHEMBL3087157 | — | — | 1 | 6.00 |
| CHEMBL3087156 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3087008 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL3087157 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3087156 | — | IC50 | = | 2560.0 | nM | 5.59 |