Assay Detail
Binding
CHEMBL3089615
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of fluorescein-labeled MS239 from recombinant human SMARCA4 bromodomain after 1 hr by fluorescence anisotropy assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.10 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3086883 | — | — | 1 | 5.10 |
| CHEMBL3086885 | — | — | 1 | - |
| CHEMBL3086884 | — | — | 1 | - |
| CHEMBL3087052 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3086883 | — | Ki | = | 7970.0 | nM | 5.10 |
| CHEMBL3086885 | — | Ki | < | 6560.0 | nM | - |
| CHEMBL3086884 | — | Ki | < | 6560.0 | nM | - |
| CHEMBL3087052 | — | Ki | < | 6560.0 | nM | - |