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Assay Detail

CHEMBL3090407

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Functional
Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Solution-phase microwave assisted parallel synthesis of N,N'-disubstituted thioureas derived from benzoic acid: biological evaluation and molecular docking studies.
Rauf MK, Talib A, Badshah A, Zaib S, Shoaib K, Shahid M, Flörke U, Imtiaz-ud-Din, Iqbal J.
Eur J Med Chem (2013) 70 : 487 -496
PubMed 24185379 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 14 4.48 4.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3087553 1 4.63
CHEMBL3087549 1 4.57
CHEMBL4296740 BUTYLATED HYDROXYANISOLE -1.0 1 4.55
CHEMBL3087545 1 4.53
CHEMBL2236349 1 4.51
CHEMBL7983 PROPYL GALLATE 1.0 1 4.39
CHEMBL3087548 1 4.16
CHEMBL3087541 1 -
CHEMBL3087557 1 -
CHEMBL3087556 1 -
CHEMBL3087554 1 -
CHEMBL3087546 1 -
CHEMBL1450561 1 -
CHEMBL1834362 N-(PHENYLCARBAMOTHIOYL)BENZAMIDE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3087553 IC50 = 23300.0 nM 4.63
CHEMBL3087549 IC50 = 27000.0 nM 4.57
CHEMBL4296740 BUTYLATED HYDROXYANISOLE IC50 = 28200.0 nM 4.55
CHEMBL3087545 IC50 = 29500.0 nM 4.53
CHEMBL2236349 IC50 = 30700.0 nM 4.51
CHEMBL7983 PROPYL GALLATE IC50 = 40800.0 nM 4.39
CHEMBL3087548 IC50 = 70000.0 nM 4.16
CHEMBL3087541 IC50 = 276000.0 nM -
CHEMBL3087557 IC50 = 676000.0 nM -
CHEMBL3087556 IC50 = 114000.0 nM -
CHEMBL3087554 IC50 = 805000.0 nM -
CHEMBL3087546 IC50 = 240000.0 nM -
CHEMBL1450561 IC50 = 265000.0 nM -
CHEMBL1834362 N-(PHENYLCARBAMOTHIOYL)BENZAMIDE IC50 = 769000.0 nM -