Assay Detail
Binding
CHEMBL3090833
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ERG
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-gated inwardly rectifying potassium channel KCNH2 (CHEMBL240) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Polypharmacology - foe or friend?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41 | FLUOXETINE | 4.0 | 1 | 8.00 |
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 8.00 |
| CHEMBL6966 | VERAPAMIL | 4.0 | 1 | 8.00 |
| CHEMBL549 | CITALOPRAM | 4.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41 | FLUOXETINE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL54 | HALOPERIDOL | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL6966 | VERAPAMIL | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL549 | CITALOPRAM | IC50 | = | 10.0 | nM | 8.00 |