Assay Detail
Functional
CHEMBL3094740
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of reactive oxygen species generation in fMLP-stimulated human polymorphonuclear leukocytes incubated for 15 mins prior to fMLP-challenge by fluorescence assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 1 | - | - |
| IC50 | 1 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3094412 | — | — | 2 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3094412 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3094412 | — | Inhibition | - | % | - |