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Assay Detail

CHEMBL3095756

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Binding
Inhibition of HDAC1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone deacetylase 1 (CHEMBL325)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain.
Seo YJ, Muench L, Reid A, Chen J, Kang Y, Hooker JM, Volkow ND, Fowler JS, Kim SW.
Bioorg Med Chem Lett (2013) 23 : 6700 -6705
PubMed 24210501 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95835 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95835 IC50 = 15.0 nM 7.82