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Assay Detail

CHEMBL3096092

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MAO-B (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.
Koch P, Akkari R, Brunschweiger A, Borrmann T, Schlenk M, Küppers P, Köse M, Radjainia H, Hockemeyer J, Drabczyńska A, Kieć-Kononowicz K, Müller CE.
Bioorg Med Chem (2013) 21 : 7435 -7452
PubMed 24139167 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.09 7.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL26138 1 7.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL26138 Ki = 80.6 nM 7.09