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Assay Detail

CHEMBL3097009

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Amewu RK, Chadwick J, Hussain A, Panda S, Rinki R, Janneh O, Ward SA, Miguel C, Burrell-Saward H, Vivas L, O'Neill PM.
Bioorg Med Chem (2013) 21 : 7392 -7397
PubMed 24148834 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.05 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2387268 1 9.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2387268 IC50 = 0.9 nM 9.05