Assay Detail
Binding
CHEMBL3097157
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human 5-HT3B receptor I183A mutant assessed as inhibition of 5-HT-induced response after 45 mins by FLIPR assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Exploring a potential palonosetron allosteric binding site in the 5-HT(3) receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.47 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1189679 | PALONOSETRON | 4.0 | 1 | 9.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1189679 | PALONOSETRON | IC50 | = | 0.34 | nM | 9.47 |