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Assay Detail

CHEMBL3097289

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SW620 cells after 24 to 72 hrs
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SW-620
Confidence 1 — Organism
Curated By Autocuration

Target

SW-620 (CHEMBL612262)
Type CELL-LINE
Organism Homo sapiens

Publication

Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experiment.
Lee YS, Choi KM, Kim W, Jeon YS, Lee YM, Hong JT, Yun YP, Yoo HS.
J Nat Prod (2013) 76 : 2195 -2202
PubMed 24308647 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
GI 1 - -
IC50 1 5.36 5.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48310 HINOKITIOL 2 5.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48310 HINOKITIOL IC50 = 4400.0 nM 5.36
CHEMBL48310 HINOKITIOL GI - -