Assay Detail
Binding
CHEMBL3097345
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human TGase2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein-glutamine gamma-glutamyltransferase (CHEMBL2730) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Tissue transglutaminase: an emerging target for therapy and imaging.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.50 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3092843 | — | — | 1 | 7.70 |
| CHEMBL3092841 | — | — | 1 | 7.52 |
| CHEMBL3092842 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3092843 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3092841 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3092842 | — | IC50 | = | 54.0 | nM | 7.27 |