Assay Detail
Binding
CHEMBL3097746
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Inhibition of porcine brain GSK-3alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Chemical synthesis and biological validation of immobilized protein kinase inhibitory Leucettines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.95 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3092863 | — | — | 1 | 6.70 |
| CHEMBL3092862 | — | — | 1 | 6.57 |
| CHEMBL1802358 | — | — | 1 | 6.14 |
| CHEMBL3092864 | — | — | 1 | 4.40 |
| CHEMBL3092861 | — | — | 1 | - |
| CHEMBL3092860 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3092863 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL3092862 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL1802358 | — | IC50 | = | 730.0 | nM | 6.14 |
| CHEMBL3092864 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL3092861 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3092860 | — | IC50 | > | 100000.0 | nM | - |