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Assay Detail

CHEMBL3097973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant MAO-B expressed in insect cells by Amplex Red assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chromenylchalcones with inhibitory effects on monoamine oxidase B.
Jo G, Ahn S, Kim BG, Park HR, Kim YH, Choo HA, Koh D, Chong Y, Ahn JH, Lim Y.
Bioorg Med Chem (2013) 21 : 7890 -7897
PubMed 24169316 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.70 8.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL972 SELEGILINE 4.0 1 8.89
CHEMBL2396876 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL972 SELEGILINE IC50 = 1.3 nM 8.89
CHEMBL2396876 IC50 = 320.0 nM 6.50