Assay Detail
Binding
CHEMBL3097976
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MAO-B (unknown origin) using p-tyramine substrate by HPLC method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chromenylchalcones with inhibitory effects on monoamine oxidase B.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.69 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL972 | SELEGILINE | 4.0 | 1 | 4.96 |
| CHEMBL2396876 | — | — | 1 | 4.86 |
| CHEMBL2396879 | — | — | 1 | 4.78 |
| CHEMBL2396880 | — | — | 1 | 4.74 |
| CHEMBL2396877 | — | — | 1 | 4.45 |
| CHEMBL2396878 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL972 | SELEGILINE | IC50 | = | 10960.0 | nM | 4.96 |
| CHEMBL2396876 | — | IC50 | = | 13710.0 | nM | 4.86 |
| CHEMBL2396879 | — | IC50 | = | 16670.0 | nM | 4.78 |
| CHEMBL2396880 | — | IC50 | = | 18300.0 | nM | 4.74 |
| CHEMBL2396877 | — | IC50 | = | 35860.0 | nM | 4.45 |
| CHEMBL2396878 | — | IC50 | = | 42770.0 | nM | 4.37 |