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Assay Detail

CHEMBL3100312

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins by spectrophotometric analysis
21
Total Activities
21
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease.
Li SY, Wang XB, Kong LY.
Eur J Med Chem (2014) 71 : 36 -45
PubMed 24269515 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 21 4.44 4.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2064671 1 4.85
CHEMBL1966239 1 4.58
CHEMBL3098345 1 4.54
CHEMBL2064673 1 4.49
CHEMBL3098342 1 4.43
CHEMBL3098344 1 4.42
CHEMBL2064668 1 4.40
CHEMBL3098343 1 4.38
CHEMBL1797961 1 4.36
CHEMBL2236145 1 4.35
CHEMBL2064669 1 4.29
CHEMBL2064670 1 4.18
CHEMBL2064674 1 -
CHEMBL205927 2-((PHENYLIMINO)METHYL)PHENOL 1 -
CHEMBL2064676 1 -
CHEMBL1797968 1 -
CHEMBL3098346 1 -
CHEMBL3098347 1 -
CHEMBL3098348 1 -
CHEMBL3098349 1 -
CHEMBL165 RESVERATROL 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2064671 IC50 = 14100.0 nM 4.85
CHEMBL1966239 IC50 = 26500.0 nM 4.58
CHEMBL3098345 IC50 = 28500.0 nM 4.54
CHEMBL2064673 IC50 = 32700.0 nM 4.49
CHEMBL3098342 IC50 = 36800.0 nM 4.43
CHEMBL3098344 IC50 = 37800.0 nM 4.42
CHEMBL2064668 IC50 = 39900.0 nM 4.40
CHEMBL3098343 IC50 = 41300.0 nM 4.38
CHEMBL1797961 IC50 = 43900.0 nM 4.36
CHEMBL2236145 IC50 = 45100.0 nM 4.35
CHEMBL2064669 IC50 = 51800.0 nM 4.29
CHEMBL2064670 IC50 = 66600.0 nM 4.18
CHEMBL2064674 IC50 > 2000000.0 nM -
CHEMBL205927 2-((PHENYLIMINO)METHYL)PHENOL IC50 > 2000000.0 nM -
CHEMBL2064676 IC50 = 398700.0 nM -
CHEMBL1797968 IC50 > 2000000.0 nM -
CHEMBL3098346 IC50 > 2000000.0 nM -
CHEMBL3098347 IC50 > 2000000.0 nM -
CHEMBL3098348 IC50 > 2000000.0 nM -
CHEMBL3098349 IC50 = 794400.0 nM -
CHEMBL165 RESVERATROL IC50 = 108600.0 nM -