Assay Detail
Functional
CHEMBL3100351
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Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antitumor potential of conjugable valinomycins bearing hydroxyl sites: in vitro studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.12 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223643 | VALINOMYCIN | — | 1 | 9.10 |
| CHEMBL3099816 | — | — | 1 | 8.37 |
| CHEMBL3099598 | — | — | 1 | 8.31 |
| CHEMBL3099817 | — | — | 1 | 6.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223643 | VALINOMYCIN | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3099816 | — | IC50 | = | 4.3 | nM | 8.37 |
| CHEMBL3099598 | — | IC50 | = | 4.9 | nM | 8.31 |
| CHEMBL3099817 | — | IC50 | = | 197.1 | nM | 6.71 |