Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3100685

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of Bacillus anthracis recombinant lethal factor expressed in Escherichia coli by linear double-reciprocal plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacillus anthracis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lethal factor (CHEMBL4372)
Type SINGLE PROTEIN
Organism Bacillus anthracis

Publication

Small molecule inhibitors of anthrax lethal factor toxin.
Williams JD, Khan AR, Cardinale SC, Butler MM, Bowlin TL, Peet NP.
Bioorg Med Chem (2014) 22 : 419 -434
PubMed 24290062 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.62 7.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL204593 1 7.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL204593 Ki = 24.0 nM 7.62