Assay Detail
Binding
CHEMBL3101060
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Inhibition of Toxoplasma gondii FPPS
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Toxoplasma gondii |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.21 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3099275 | — | — | 1 | 7.46 |
| CHEMBL3099279 | — | — | 1 | 7.41 |
| CHEMBL3099278 | — | — | 1 | 7.29 |
| CHEMBL3099276 | — | — | 1 | 7.22 |
| CHEMBL3099277 | — | — | 1 | 7.17 |
| CHEMBL261473 | — | — | 1 | 7.02 |
| CHEMBL3099280 | — | — | 1 | 6.90 |
| CHEMBL2326224 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3099275 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL3099279 | — | IC50 | = | 39.0 | nM | 7.41 |
| CHEMBL3099278 | — | IC50 | = | 51.0 | nM | 7.29 |
| CHEMBL3099276 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL3099277 | — | IC50 | = | 67.0 | nM | 7.17 |
| CHEMBL261473 | — | IC50 | = | 95.0 | nM | 7.02 |
| CHEMBL3099280 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL2326224 | — | IC50 | > | 1000.0 | nM | - |