Assay Detail
Functional
CHEMBL3101280
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Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
7,7'-Diazaindirubin--a small molecule inhibitor of casein kinase 2 in vitro and in cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.63 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3099673 | — | — | 1 | 6.30 |
| CHEMBL1076931 | — | — | 1 | 5.52 |
| CHEMBL1276127 | INDIRUBIN | 2.0 | 1 | 5.40 |
| CHEMBL3099674 | — | — | 1 | 5.30 |
| CHEMBL3099676 | — | — | 1 | - |
| CHEMBL3099675 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3099673 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL1076931 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1276127 | INDIRUBIN | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL3099674 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3099676 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3099675 | — | IC50 | > | 100000.0 | nM | - |