Assay Detail
Binding
CHEMBL3102108
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Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured for 30 minutes by fluorescence assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exploring the chemical space of multitarget ligands using aligned self-organizing maps.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.69 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3099680 | — | — | 1 | 6.77 |
| CHEMBL1313977 | — | — | 1 | 5.52 |
| CHEMBL3099590 | — | — | 1 | 4.75 |
| CHEMBL3099593 | — | — | 1 | 4.24 |
| CHEMBL1594316 | — | — | 1 | 4.12 |
| CHEMBL3099591 | — | — | 1 | 4.04 |
| CHEMBL83103 | — | — | 1 | 4.04 |
| CHEMBL3099592 | — | — | 1 | 4.02 |
| CHEMBL3099679 | — | — | 1 | - |
| CHEMBL3099678 | — | — | 1 | - |
| CHEMBL201094 | FUBERIDAZOLE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3099680 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL1313977 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3099590 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL3099593 | — | IC50 | = | 57000.0 | nM | 4.24 |
| CHEMBL1594316 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL3099591 | — | IC50 | = | 91000.0 | nM | 4.04 |
| CHEMBL83103 | — | IC50 | = | 91000.0 | nM | 4.04 |
| CHEMBL3099592 | — | IC50 | = | 95000.0 | nM | 4.02 |
| CHEMBL3099679 | — | IC50 | = | 133000.0 | nM | - |
| CHEMBL3099678 | — | IC50 | = | 379000.0 | nM | - |
| CHEMBL201094 | FUBERIDAZOLE | IC50 | = | 207000.0 | nM | - |