Assay Detail
Binding
CHEMBL3102177
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human dopamine D3 receptor
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of 2,5-diarylnicotinamides as selective orexin-2 receptor antagonists (2-SORAs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.49 | 5.49 |
| IC50 | 1 | 5.02 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3099899 | — | — | 2 | 5.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3099899 | — | Ki | = | 3240.0 | nM | 5.49 |
| CHEMBL3099899 | — | IC50 | = | 9540.0 | nM | 5.02 |