Assay Detail
Binding
CHEMBL3106536
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Displacement of [3H]-DTG from sigma-2 receptor in human RT4 cell homogenates in presence of (+)-pentazocine
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | RT-4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Involvement of apoptosis and autophagy in the death of RPMI 8226 multiple myeloma cells by two enantiomeric sigma receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.39 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3104857 | — | — | 1 | 7.41 |
| CHEMBL3104856 | — | — | 1 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3104857 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL3104856 | — | Ki | = | 43.0 | nM | 7.37 |