Assay Detail
Binding
CHEMBL3106965
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Inhibition of aromatase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.05 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274318 | FLAVANONE | — | 1 | 5.10 |
| CHEMBL275638 | FLAVONE | 2.0 | 1 | 5.00 |
| CHEMBL366460 | ISOFLAVONE | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274318 | FLAVANONE | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL275638 | FLAVONE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL366460 | ISOFLAVONE | IC50 | - | — | - |