Assay Detail
Binding
CHEMBL3108316
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SRC (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.02 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | — | 1 | 7.40 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 6.92 |
| CHEMBL3104851 | — | — | 1 | 6.43 |
| CHEMBL3104855 | — | — | 1 | 6.31 |
| CHEMBL3104854 | — | — | 1 | 5.45 |
| CHEMBL3104852 | — | — | 1 | 4.90 |
| CHEMBL3104853 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL50 | QUERCETIN | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL3104851 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL3104855 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL3104854 | — | IC50 | = | 3560.0 | nM | 5.45 |
| CHEMBL3104852 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL3104853 | — | IC50 | = | 20000.0 | nM | 4.70 |