Assay Detail
Binding
CHEMBL3108406
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Inhibition of MAO-A (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.87 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3989843 | TRANYLCYPROMINE | 4.0 | 1 | 5.68 |
| CHEMBL199600 | — | — | 1 | 4.05 |
| CHEMBL3104250 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3989843 | TRANYLCYPROMINE | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL199600 | — | IC50 | = | 88500.0 | nM | 4.05 |
| CHEMBL3104250 | — | IC50 | > | 300000.0 | nM | - |