Assay Detail
Binding
CHEMBL3110586
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Inhibition of ARTD1 (unknown origin)
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evaluation and Structural Basis for the Inhibition of Tankyrases by PARP Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.70 | 7.70 |
| IC50 | 1 | 7.35 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL372303 | PJ34 | — | 1 | 7.70 |
| CHEMBL435073 | — | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL372303 | PJ34 | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL435073 | — | IC50 | = | 45.0 | nM | 7.35 |