Assay Detail
Functional
CHEMBL3110794
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiprotozoal activity against Entamoeba histolytica HM-1:IMSS
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Entamoeba histolytica |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure, absolute configuration, and antidiarrheal activity of a thymol derivative from Ageratina cylindrica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.15 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 6.64 |
| CHEMBL50588 | EMETINE | 4.0 | 1 | 5.66 |
| CHEMBL206452 | CATECHIN | — | 1 | - |
| CHEMBL3109435 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL50588 | EMETINE | IC50 | = | 2180.0 | nM | 5.66 |
| CHEMBL206452 | CATECHIN | IC50 | = | 225900.0 | nM | - |
| CHEMBL3109435 | — | IC50 | = | 184900.0 | nM | - |