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Assay Detail

CHEMBL3124159

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HOP92 cells after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HOP-92
Confidence 1 — Organism
Curated By Autocuration

Target

HOP-92 (CHEMBL613889)
Type CELL-LINE
Organism Homo sapiens

Publication

Benzofuran derivatives as a novel class of inhibitors of mTOR signaling.
Salomé C, Narbonne V, Ribeiro N, Thuaud F, Serova M, de Gramont A, Faivre S, Raymond E, Désaubry L.
Eur J Med Chem (2014) 74 : 41 -49
PubMed 24445311 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.40 4.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL526034 1 4.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL526034 IC50 = 40000.0 nM 4.40